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Volume 21, Number 1, 2016

Toxic epidermal necrolysis associated with radiotherapy and phenytoin in a patient with non-Hodking's lymphoma: A case report

Fatma Keklik, Melda Cömert Özkan, Gizem Kocabaş Yenipazar, Banu Yaman, Güray Saydam, Fahri Şahin


Toxic epidermal necrolysis (TEN) is a disease which is characterized by fever and desquamation of the skin and mucosal membranes. It is usually related with drugs, especially aromatic anticonvulsants which are recognized as the most common cause of this disorder. Cranial irradiation may act as a precipitating factor along with anticonvulsants for the development of TEN. We report a 28-year-old patient with central nervous system (CNS) relapsed non-Hodgkin lymphoma (NHL) who developed TEN after cranial radiotherapy and concurrent phenytoin treatment.

Signature: Rep Pract Oncol Radiother, 2016; 21(1) : 81-83

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