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Volume 21, Number 4, 2016

Treatment of endolymphatic sac tumour (Papillary adenocarcinoma) of the temporal bone

Arturo Mario Poletti, Siba Prasad Dubey, Giovanni Colombo, Giovanni Cugini, Antonio Mazzoni

Summary:

Aim

To define a better treatment of sporadic endolymphatic sac tumours (ELST) analysing our experience and literature available data.

Background

ELST can arise as sporadic case (rare) or as a part of von Hippel–Lindau (VHL) disease. It is a low grade malignancy with local spread by continuity.

Materials and methods

we described our experience with 7 cases with up to date follow up.

Results

Five cases were free of disease after first surgical procedure. One case had recurrence in the temporal lobe after 12 years. One case had two surgical procedures followed by irradiation and died five years after radiotherapy with a slow disease progression.

Conclusion

With increasing expertise in the skull base surgery, complete tumour excisions are achieved in majority of the more recent cases and appear to be the treatment of choice. External irradiation is also used as palliative measures with doubtful effectiveness. Some recent reports showed encouraging results with gamma knife radiosurgery.

Signature: Rep Pract Oncol Radiother, 2016; 21(4) : 391-394


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Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.

http://www.sciencedirect.com/science/journal/15071367/19/2