Dear Authors,
If you believe that your paper was mistakenly rejected by other leading journals and you do not agree with final decision, the editors of Reports of Practical Oncology and Radiotherapy offer new fast track review. You may submit your manuscript to Reports of Practical Oncology and Radiotherapy together with all prior peer-reviews obtained from the other journal and your rebuttal letter. We guarantee review based decision within 72 hours from the time we will receive your manuscript.

Fast track submission process: Please submit the manuscript with all reviews and rebuttal letter by email to Dr. Michal Masternak ( for fast review processing. To assure immediate attention the email title must to include: RPOR-fast track- Last Name First Name (of corresponding author).

Volume 6, Number 1, 2001

Impact of HB level during postoperative radiotherapy of patients with larynx cancer

Milecki P, Nawrocki S, Stryczyńska G, Kruk-Zagajewska A, Fundowicz D.


Aim: assessment the influence of low level of Hgb on the locoregional outcome of postoperative radiotherapy patients with advanced cancer of larynx.

Material and methods: An retrospective analysis of two hundred fifty four patients with larynx carcinoma with stage III or IV squamous cell carcinoma of larynx who were treated between January 1993 and December 1996 was performed. Postoperative radiotherapy was performed in coventional way to total dose of 60 Gy, 5 times a week. Of 254 patients, 86 patients (34%) were considered to have a low level of hemoglobin (below 13 g/dl) prior the beginning of radiotherapy and 56 patients (22%) at the end of treatment. We have noted also 38 patients (15%) of 254 patients, with deacresing hemoglobin level during treatment higher than 1 g/dl.

Results: No impact on outcome of treatment was observed in the group of patients with low level of Hgb before irradiation. Inrease of locoregional failure of postoperative radiotherapy was noted in group of patients with Hgb level at the end of irradiation below 13 g/dl (p = 0,004) and also in group of patients with decreasing of Hgb level during treatment (p = 0,038).

Conclusions: Low Hgb levels at the end of postoperative irradiation and decreasing during irradiation were associated with a statistically significant an increase in locoregional failure of patients with advanced carcinoma of larynx.

Signature: Rep Pract Oncol Radiother, 2001; 6(1) : 47-48

« back


Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.