Dear Authors,
If you believe that your paper was mistakenly rejected by other leading journals and you do not agree with final decision, the editors of Reports of Practical Oncology and Radiotherapy offer new fast track review. You may submit your manuscript to Reports of Practical Oncology and Radiotherapy together with all prior peer-reviews obtained from the other journal and your rebuttal letter. We guarantee review based decision within 72 hours from the time we will receive your manuscript.

Fast track submission process: Please submit the manuscript with all reviews and rebuttal letter by email to Dr. Michal Masternak ( for fast review processing. To assure immediate attention the email title must to include: RPOR-fast track- Last Name First Name (of corresponding author).

Volume 10, Number 3, 2005

Does interstitial HDR brachytherapy for breast cancer increase soft tissue fibrosis?

Anna Wronczewska, Roman Makarewicz, Renata Kabacińska, Anysja Zuchora


Aim To analyze the physical parameters of interstitial HDR brachytherapy and their influence on the risk of soft tissue fibrosis.
Materials/Methods A retrospective analysis of 54 breast cancer patients treated between 1994–1999 in the Brachytherapy Department of the Oncological Centre in Bydgoszcz was performed. Minimum follow up period was 41 months and the maximum was 89 months. The mean follow up period was 65 months. Owing to statiscally significant differences between the groups, when compared to a normal distribution, the U Mann-Whitney non-parametrical test was used as the method for comparison.
Results Out of the nine parameters analysed, three were found to be associated with increased risk of fibrosis occurrence. Reference volumes V100, V150 and V200 showed statistically signifi cant differences (p<0.05).
Conclusions In breast conserving therapy a number of parameters influence the results of treatment. Our own studies have shown that among the risk factors responsible for fibrosis are: reference volume V100 (the volume of tissue surrounded by 100% isodose), V150 (volume of tissue surrounded by 150% isodose) and V200 (volume of tissue surrounded by 200% isodose).

Signature: Rep Pract Oncol Radiother, 2005; 10(3) : 119-123


« back


Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.