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Volume 15, Number 4, 2010

CYBERKNIFE : A double edged sword ?

Bindhu Joseph,  Sanjay Supe,  Aruna Ramachandra

Summary:

Cyberknife represents a new, frameless stereotactic radiosurgery system which efficiently incorporates advance robotics with computerized image reconstruction to allow highly
conformal image guided radiation delivery. This review focuses on the pros and cons of this new radiotherapy tool, its current indications, safety profile and future directions. Datebases of
Medline, Pubmed, Biomed, Medscape and Cancer Lit have been referred to in order to retrieve relevent data/information. The authors conclude that the use of this system offers an invaluable solution to the treatment of selective tumours/ lesions located close to critical structures, salvage of recurrent and metastatic lesions, and potential for treatment of selective early stage malignancies, like carcinoma of the prostate and carcinoma of the Lungs. However, the system is still too premature, with insufficient follow up data, to advocate it as the treatment of choice in any set up. There are several radiobiological issues that also remain in the grey zone.

Signature: Rep Pract Oncol Radiother, 2010; 15(4) : 93-97


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INDEXED IN:

Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.

http://www.sciencedirect.com/science/journal/15071367/19/2