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Volume 15, Number 4, 2010

Psoriasis exacerbation after hormonotherapy in prostate cancer patient - case report.

Marta Biedka, Ewa Ziółkowska,  Agnieszka Żyromska,  Roman Makarewicz

Summary:

Psoriasis, as the most common inflammatory skin disorder, affects about 2%-3% of the
world's population. Many non-dermatological conditions have been linked with psoriasis, including cardiovascular diseases, depression, inflammatory bowel disorders, and some cancers, i.e. lung, colon and kidney cancers. Among systemic factors are endocrine and metabolic disturbances as well as many drugs. Erythrodermic psoriasis, the most severe form of the disease, is characterized by diffuse erytrema and scaling, often accompanied by fever, chills, and malaise. Patients with serve cases of erythrodermic psoriasis may have hypothermia and hypoalbuminemia secondary to skin exfoliation.
To our best knowledge hormone therapy (androgen deprivation) of prostate cancer patients has not been reported as an aggravating factor. Thus, the aim of our work is to present the case of a prostate cancer patient who experienced psoriasis exacerbation after implementation of hormonal blockade as a neoadjuvant oncological treatment.

Signature: Rep Pract Oncol Radiother, 2010; 15(4) : 103-106


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Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.

http://www.sciencedirect.com/science/journal/15071367/19/2