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Volume 17, Number 6, 2012

Primary squamous cell carcinoma of the breast: A rare case report

Stefania Carbone, Rosabel Lobo Alvarez, Annalisa Lamacchia, Asuncion Almenar Gil, Raquel Martin Hernandez, Jose Luis Lopez Guerra, Hugo Marsiglia

Summary:

Background

Squamous cells are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of the breast is an exceptional phenomenon and the management of this type of disease is still debated.

Aim

Clinical outcome assessment of a patient with squamous cell carcinoma of the breast.

Materials and methods

We report a case of primary squamous cell carcinoma of the breast (T1cN0M0) in a 51-years-old woman who underwent breast conserving surgery plus adjuvant chemotherapy and radiation therapy (RT).

Results

With a follow up of 43 months, the patient is alive with no evidence of local or distant recurrence. The patient had Grade 2 acute skin toxicity. No late skin or respiratory toxicity was observed.

Conclusions

Pure primary squamous cell carcinoma of the breast is a rare and aggressive disease, often treatment-refractory. Our case shows that the addition of RT after breast conserving surgery, allows to achieve a high local control without adding severe toxicity. A multidisciplinary approach seems to be the optimal management for early stages in this rare disease.

Signature: Rep Pract Oncol Radiother, 2012; 17(6) : 363-366


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Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.

http://www.sciencedirect.com/science/journal/15071367/19/2