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Volume 18, Number 4, 2013

Empirical estimation of beam-on time for prostate cancer patients treated on Tomotherapy

Małgorzata Skórska, Tomasz Piotrowski


Background and aim: This study proposed a method to estimate the beam-on time for prostate
cancer patients treated on Tomotherapy when FW (field width), PF (pitch factor), modulation
factor (MF) and treatment length (TL) were given.
Material and methods: The study was divided into two parts: building and verifying the model.
To build a model, 160 treatment plans were created for 10 patients. The plans differed in
combination of FW, PF and MF. For all plans a graph of beam-on time as a function of TL was
created and a linear trend function was fitted. Equation for each trend line was determined
and used in a correlation model. Finally, 62 plans verified the treatment time computation
model – the real execution time was compared with our estimation and irradiation time
calculated based on the equation provided by the manufacturer.
Results: A linear trend function was drawn and the coefficient of determination R2 and the
Pearson correlation coefficient r were calculated for each of the 8 trend lines corresponding
to the adequate treatment plan. An equation to correct the model was determined to
estimate more accurately the beam-on time for different MFs. From 62 verification treatment
plans, only 5 disagreed by more than 60 s with the real time from the HT software.
Whereas, for the equation provided by the manufacturer the discrepancy was observed in
16 cases.
Conclusions: Our study showed that the model can well predict the treatment time for a given
TL, MF, FW and it can be used in clinical practice.

Signature: Rep Pract Oncol Radiother, 2013; 18(4) : 201-208

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