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Volume 18, Number 4, 2013

Correlation between clinical findings and magnetic resonance imaging for the assessment of local response after standard treatment in cervical cancer

Izaskun Valduvieco, Albert Biete, Iván Rios, Ricardo Llorente, Angels Rovirosa, Jaume Pahisa, Laura Vidal, Blanca Farrús, Pilar Samper

Summary:

Background: The aim of our study is to evaluate the correlation between gynecological examination and magnetic resonance (MRI) findings for the assessment of local response in
cervical cancer patients treated with radiotherapy/chemotherapy (RT/ChT).
Patients and methods: This study is a retrospective review of 75 consecutive cervical cancer
patients from April 2004 to November 2009 treated with RT/ChT. Clinical and radiological
data were subsequently analyzed. Patient’s median age was 51 with a FIGO stage from
Ib to IVb. Individualized RT/ChT was administered with a median dose of 45 Gy. Sixtythree
patients received a complementary brachytherapy. Seventy-one patients received
chemotherapy on a weekly basis. Gynecological exam was performed 3 months and 6
months after treatment and these findings were compared to MRI results at the same time.
Statistic analysis: We used the Spearman’s Rho test to determine the correlation level between
the clinical and radiological methods.
Results: A correlation of 0.68 (60%) was observed between the clinical and MRI findings at 3
months with a further increase of up to 0.86 (82.6%) at 6 months. In the few cases with a
poor correlation, the subsequent assessment and the natural history of the disease showed
a greater value of the clinical exam as compared with the MRI findings.

Signature: Rep Pract Oncol Radiother, 2013; 18(4) : 214-219


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Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.

http://www.sciencedirect.com/science/journal/15071367/19/2