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Volume 19, Number 2, 2014

First treatment of mycosis fungoides by total skin electron beam (TSEB) therapy in Greece

Stefanos Diamantopoulos, Kalliopi Platoni, Vassilis Kouloulias, Panayiotis Pantelakos, Maria Dilvoi, Evangelia Papadav



Mycosis fungoides (MF), the most common subtype of cutaneous T-Cell Lymphoma (CTCL), is a rare chronic skin neoplasia. Total skin electron irradiation has been employed along with a variety of other topical or systemic treatments for MF management.


To report the first case treated by TSEB irradiation protocol in Greece.

Materials and methods

A fractionated 36 Gy total skin electron beam (TSEB) therapy was prescribed to a 65-years-old male patient with mycosis fungoides (MF), stage IIB, refractory to several treatments during a 20-year period. Dose uniform delivery was monitored by thermo-luminescence dosimetry.

Results and discussion

The homogeneous skin dose distribution resulted in a complete clinical response. Limited, irradiation-oriented, side effects appeared.


The first TSEB irradiation prescription in Greek medical chronicles was proved effective in this case of tumor stage MF (T3-IIB), which had been refractory to several single or combination treatments.

Signature: Rep Pract Oncol Radiother, 2014; 19(2) : 114-119

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